In Vitro Fertilization (IVF) has helped millions of families worldwide fulfill their dream of having children. Since the birth of the first IVF baby in 1978, scientific advancements have transformed IVF into a safe and reliable option for individuals facing fertility challenges. But how does IVF impact the health of babies born through this method?

The Evolution of Assisted Reproduction Techniques
Since 1978, assisted reproductive technology has progressed significantly. Techniques like ICSI (Intracytoplasmic Sperm Injection)—which involves injecting a single sperm directly into an egg—have become invaluable for addressing severe male infertility. Similarly, PICSI (Physiological ICSI) selects mature sperm based on their affinity for hyaluronic acid, improving fertilization success rates while reducing genetic risks.
Advancements like Preimplantation Genetic Testing (PGT-A), combined with state-of-the-art laboratories, ensure increasingly personalized and safe care for parents and their future children.
What does Science have to say about IVF children?
Research consistently shows that babies born via IVF are just as healthy as those conceived naturally. Studies report no significant differences in physical, cognitive, or emotional development. However, there is a slightly increased risk of preterm birth or low birth weight in some cases, which is more often linked to maternal age or preexisting conditions rather than the IVF process itself.
Are IVF Babies Different?
No, babies born through IVF are no different in health, physical development, or emotional well-being compared to naturally conceived children. Decades of research affirm that children born through assisted reproductive techniques lead lives just as fulfilling as their peers.
A common question for prospective parents is whether different assisted reproduction methods, such as IUI (Intrauterine Insemination) or IVF with ICSI, impact a child’s quality of life.

Comparing Assisted Reproductive Methods
- IVF vs. IUI
IUI involves placing sperm directly into the uterus during ovulation, with no direct manipulation of eggs or embryos. Babies conceived through IUI develop just as naturally as those conceived spontaneously. IVF, by contrast, fertilizes the egg outside the body and allows for the selection of the most viable embryos. Both methods can result in healthy children. - IVF with ICSI
For severe male infertility, ICSI ensures fertilization by directly injecting a sperm cell into an egg. Studies show no significant differences in the development of children born via ICSI compared to those conceived through other methods or naturally. - IVF with Genetic Testing
PGT-A screens embryos for genetic abnormalities before implantation, increasing pregnancy success rates and reducing the risk of genetic conditions. This ensures healthy outcomes for the baby.

Other Frequently Asked Questions
Does the method of conception affect a child’s longevity?
No. Research confirms that life expectancy for children conceived via IVF or IUI is comparable to those conceived naturally.
How does parental health influence the baby’s development?
The parents’ health and age significantly affect the baby’s development, often more than the method of conception.
Full and Healthy Lives
Since 1978, millions of individuals conceived via IVF have grown up to lead fulfilling lives, form families, and achieve remarkable goals. Louise Brown, the first IVF baby, exemplifies this—she is now a mother of two naturally conceived children.
Choosing IVF is a significant decision that should be informed by reliable information and guidance from fertility specialists. If you are considering this path, it’s natural to have questions. At Nascere, we’re here to help you explore your options and support your journey to bringing a long-awaited baby into your family.